Publications

Title First Author Journal Date PMID DOI More Information
The kinetics of E-selectin- and P-selectin-induced intermediate activation of integrin αLβ2 on neutrophils. Fangyuan Zhou, Fang Zhang Journal of cell science 9/23/2021 11023892 10.1242/jcs.258046 More Info
Distinct roles of ICOS and CD40L in human T-B cell adhesion and antibody production. Zhicui Liu, Shuai Liu, Yan Zhang, Weihong Zeng, Shujun Wang, Ping Ji, Meng Pan, Cheng Zhu, Ying Wang Cellular immunology 8/6/2021 34418679 10.1016/j.cellimm.2021.104420 More Info
Neuromechanobiology: An Expanding Field Driven by the Force of Greater Focus. Cara T Motz, Victoria Kabat Advanced Healthcare Materials 8/2/2021 14012334 10.1002/adhm.202100102 More Info
PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition. Kaitao Li Nature communications 5/12/2021 15358536 10.1038/s41467-021-22965-9 More Info
From cellular to molecular mechanobiology. Cheng Zhu APL bioengineering 2/14/2020 31965350 10.1063/1.5129937 More Info
Mechanotransduction in T Cell Development, Differentiation and Function. Muaz Rushdi, Kaitao Li Cells 2/5/2020 26051539 10.3390/cells9020364 More Info
Calibration for computer experiments with binary responses and application to cell adhesion study Chih-Li Sung, Ying Hung, William Rittase, Cheng Zhu, CF Wu Journal of the American Statistical Association 1/21/2020 None 10.1080/01621459.2019.1699419 More Info
Mechanochemical coupling of formin-induced actin interaction at the level of single molecular complex. Zhenhai Li, Hyunjung Lee, Suzanne G. Eskin, Shoichiro Ono, Cheng Zhu, Larry V. McIntire Biomechanics and modeling in mechanobiology 1/21/2020 12525176 10.1007/s10237-019-01284-5 More Info
Single-molecule investigations of T-cell activation. Kaitao Li, William Rittase Current opinion in biomedical engineering 11/1/2019 27192323 10.1016/j.cobme.2019.10.005 More Info
Dynamic bonds and their roles in mechanosensing. Cheng Zhu Current opinion in chemical biology 9/27/2019 27065098 10.1016/j.cbpa.2019.08.005 More Info
Mechanosensing through immunoreceptors. Cheng Zhu Nature immunology 9/18/2019 31534240 10.1038/s41590-019-0491-1 More Info
Domain-specific mechanical modulation of VWF-ADAMTS13 interaction. Zhenhai Li Molecular biology of the cell 7/19/2019 31067148 10.1091/mbc.E19-01-0021 More Info
A Generalized Gaussian Process Model for Computer Experiments With Binary Time Series Chih-Li Sung, Ying Hung, William Rittase, Cheng Zhu, C. F. Jeff Wu Journal of the American Statistical Association 5/28/2019 None 10.1080/01621459.2019.1604361 More Info
Abstract 3236: T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade Duane Moogk, Lin Wang, Kaitao Li, Zhou Yuan, Jeffrey Weber, Iman Osman, Cheng Zhu and Michelle Krogsgaard AACR; Cancer Res 3/29/2019 None 10.1158/1538-7445.AM2019-3236 More Info
An integrin αIIbβ3 intermediate affinity state mediates biomechanical platelet aggregation. Yunfeng Chen Nature materials 3/25/2019 30911119 10.1038/s41563-019-0323-6 More Info
Force-history dependence and cyclic mechanical reinforcement of actin filaments at the single molecular level. Hyunjung Lee, Suzanne G. Eskin, Shoichiro Ono, Cheng Zhu, Larry V. McIntire Journal of Cell Science 2/4/2019 30659118 10.1242/jcs.216911 More Info
Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition. Peng Wu Molecular cell 1/30/2019 30711376 10.1016/j.molcel.2018.12.018 More Info
Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment. Gurpanna Saggu Nature communications 11/29/2018 23310953 10.1038/s41467-018-07506-1 More Info
A TCR mechanotransduction signaling loop induces negative selection in the thymus. Jinsung Hong Nature immunology 11/12/2018 30420628 10.1038/s41590-018-0259-z More Info
Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis. Xiaohong Ruby Xu Nature communications 9/6/2018 7923659 10.1038/s41467-018-05806-0 More Info
Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces. Palash K Dutta Nano letters 7/5/2018 27941751 10.1021/acs.nanolett.8b01374 More Info
Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces. Palash K Dutta Nano letters 7/5/2018 29911385 10.1021/acs.nanolett.8b01374 More Info
Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release and coagulation. Aiming Pang Blood 5/31/2018 29853537 10.1182/blood-2017-05-785253 More Info
Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets. Lining Ju Nature communications 3/14/2018 18071073 10.1038/s41467-018-03430-6 More Info
Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets. Lining Ju Nature communications 3/14/2018 29540687 10.1038/s41467-018-03430-6 More Info
Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species. Lining Ju Scientific reports 10/27/2017 29079742 10.1038/s41598-017-13793-3 More Info
Receptor-mediated cell mechanosensing. Yunfeng Chen Molecular biology of the cell 9/27/2017 28954860 10.1091/mbc.E17-04-0228 More Info
Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases. Hiroshi Nishi The Journal of clinical investigation 9/11/2017 28891817 10.1172/JCI94039 More Info
L-selectin mechanochemistry restricts neutrophil priming in vivo. Zhenghui Liu Nature communications 5/12/2017 28497779 10.1038/ncomms15196 More Info
In situ and in silico kinetic analyses of programmed cell death-1 (PD-1) receptor, programmed cell death ligands, and B7-1 protein interaction network. Kaitao Li The Journal of biological chemistry 3/6/2017 28270509 10.1074/jbc.M116.763888 More Info
Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes. Lining Ju Methods in molecular biology (Clifton, N.J.) 3/3/2017 28255706 10.1007/978-1-4939-6881-7_15 More Info
Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity. Vincent C Luca Science (New York, N.Y.) 3/2/2017 28254785 10.1126/science.aaf9739 More Info
The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy. Guangheng Zhu Blood 1/25/2017 28122739 10.1182/blood-2016-07-729400 More Info
Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force. Padmaja Mehta-D'souza The Journal of biological chemistry 12/23/2016 28011641 10.1074/jbc.M116.767186 More Info
Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals. Lining Ju eLife 7/19/2016 27434669 10.7554/eLife.15447 More Info
Force regulated conformational change of integrin αVβ3. Yunfeng Chen Matrix biology : journal of the International Society for Matrix Biology 7/14/2016 27423389 10.1016/j.matbio.2016.07.002 More Info
Force regulated conformational change of integrin αVβ3. Yunfeng Chen Matrix biology : journal of the International Society for Matrix Biology 7/14/2016 27423389 10.1016/j.matbio.2016.07.002 More Info
Imaging Spatiotemporal Activities of ZAP-70 in Live T Cells Using a FRET-Based Biosensor. Kaitao Li Annals of biomedical engineering 7/6/2016 27384937 10.1007/s10439-016-1683-6 More Info
Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets. Duane Moogk Journal of immunology (Baltimore, Md. : 1950) 6/6/2016 27271569 10.4049/jimmunol.1600178 More Info
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. David K Cole The Journal of clinical investigation 5/16/2016 27183389 10.1172/JCI85679 More Info
Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. Alberto Elosegui-Artola Nature cell biology 4/11/2016 27065098 10.1038/ncb3336 More Info
Force-Induced Unfolding of Leucine-Rich Repeats of Glycoprotein Ibα Strengthens Ligand Interaction. Lining Ju Biophysical journal 11/5/2015 26536255 10.1016/j.bpj.2015.08.050 More Info
Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease. Jennifer D Hood Journal of immunology (Baltimore, Md. : 1950) 9/18/2015 26385521 10.4049/jimmunol.1501464 More Info
Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells. Jinsung Hong Journal of immunology (Baltimore, Md. : 1950) 9/2/2015 26336148 10.4049/jimmunol.1501407 More Info
Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell Yunfeng Chen J Vis Exp. 8/4/2015 26274371 10.3791/52975 More Info
Von Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kinetics. Lining Ju Thrombosis research 6/20/2015 26213126 10.1016/j.thromres.2015.06.019 More Info
Pre-TCR ligand binding impacts thymocyte development before αβTCR expression. Robert J Mallis Proceedings of the National Academy of Sciences of the United States of America 6/8/2015 26056289 10.1073/pnas.1504971112 More Info
The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex. Baoyu Liu European journal of immunology 5/22/2015 25944482 10.1002/eji.201445358 More Info
Transport regulation of two-dimensional receptor-ligand association. Lining Ju Biophysical journal 4/12/2015 25863068 10.1016/j.bpj.2015.02.023 More Info
A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force. Florencia Rosetti Cell reports 3/11/2015 25772353 10.1016/j.celrep.2015.02.037 More Info
Molecular force spectroscopy on cells. Baoyu Liu Annual review of physical chemistry 1/12/2015 25580628 10.1146/annurev-physchem-040214-121742 More Info
Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor. Javier Casas Nature communications 11/27/2014 25427562 10.1038/ncomms6624 More Info
DNA-based digital tension probes reveal integrin forces during early cell adhesion. Yun Zhang Nature communications 10/24/2014 25342432 10.1038/ncomms6167 More Info
A generalizable, tunable microfluidic platform for delivering fast temporally varying chemical signals to probe single-cell response dynamics. Loice Chingozha Analytical chemistry 10/10/2014 25254360 10.1021/ac5019843 More Info
Dynamic catch of a Thy-1-α5β1+syndecan-4 trimolecular complex. Vincent F Fiore Nature communications 9/12/2014 25216363 10.1038/ncomms5886 More Info
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. Baoyu Liu Cell 7/17/2014 24725404 10.1016/j.cell.2014.02.053 More Info
Accumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells. Sergey Pryshchep Journal of immunology (Baltimore, Md. : 1950) 6/2/2014 24890718 10.4049/jimmunol.1303436 More Info
Mechanical regulation of T-cell functions. Wei Chen Immunological reviews 5/8/2014 24117820 10.1111/imr.12122 More Info
Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis. Young I Choi Proceedings of the National Academy of Sciences of the United States of America 12/16/2013 24344262 10.1073/pnas.1314209111 More Info
2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system. Baoyu Liu European journal of immunology 10/20/2013 24114747 10.1002/eji.201343774 More Info
The N-terminal flanking region of the A1 domain regulates the force-dependent binding of von Willebrand factor to platelet glycoprotein Ibα. Lining Ju The Journal of biological chemistry 9/23/2013 24062306 10.1074/jbc.M113.504001 More Info
Mechanochemitry: a molecular biomechanics view of mechanosensing. Cheng Zhu Annals of biomedical engineering 9/5/2013 24006131 10.1007/s10439-013-0904-5 More Info
Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling. Yolande Chen Blood 7/23/2013 23881916 10.1182/blood-2013-03-484550 More Info
Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network. Cheng Zhu Immunological reviews 6/28/2013 23278740 10.1111/imr.12016 More Info
An HMM-based algorithm for evaluating rates of receptor-ligand binding kinetics from thermal fluctuation data. Lining Ju Bioinformatics (Oxford, England) 4/18/2013 23599504 10.1093/bioinformatics/btt180 More Info
Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds. Cho-yin Lee Proceedings of the National Academy of Sciences of the United States of America 3/4/2013 23460697 10.1073/pnas.1218407110 More Info
P-selectin glycoprotein ligand-1 forms dimeric interactions with E-selectin but monomeric interactions with L-selectin on cell surfaces. Yan Zhang PloS one 2/25/2013 23451187 10.1371/journal.pone.0057202 More Info
Cyclic mechanical reinforcement of integrin-ligand interactions. Fang Kong Molecular cell 2/14/2013 23416109 10.1016/j.molcel.2013.01.015 More Info
Insights from in situ analysis of TCR–pMHC recognition: response of an interaction network Cheng Zhu Immunological Reviews 1/1/2013 23278740 10.1111/imr.12016. More Info
Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells Wei Chen The journal of cell biology 10/29/2012 23109670 10.1083/jcb.201201091. More Info
T cell antigen recognition at the cell membrane Jun Huang Molecular Immunology 10/1/2012 22683645 10.1016/j.molimm.2012.05.004. More Info
Cellular and molecular bioengineering: A tipping point Genevieve Brown Cellular and molecular bioengineering 9/1/2012 23264805 10.1007/s12195-012-0246-7 More Info
Tyrosine Replacement of PSGL-1 Reduces Association Kinetics with P- and L-Selectin on the Cell Membrane Botao Xiao Biophysical Journal 8/22/2012 22947939 10.1016/j.bpj.2012.07.028. More Info
T cell triggering: insights from 2D kinetics analysis of molecular interactions Veronika Zarnitsyna Physical Biology 8/9/2012 22871794 10.1088/1478-3975/9/4/045005. More Info
Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters Lindsay J. Edwards Frontiers in Immunology 4/20/2012 22566966 10.3389/fimmu.2012.00086. More Info
Low 2-Dimensional CD4 T Cell Receptor Affinity for Myelin Sets in Motion Delayed Response Kinetics Kristen M. Rosenthal PLOS ONE 3/7/2012 22412888 10.1371/journal.pone.0032562. More Info
T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Jarrett J Adams Immunity 1/18/2012 22101157 10.1016/j.immuni.2011.09.013 More Info
A FRET-based biosensor for imaging SYK activities in living cells Xue Xiang Cellular and molecular bioengineering 12/4/2011 25541586 10.1007/s12195-011-0211-x More Info
Structural Basis and Kinetics of Force-Induced Conformational Changes of an αA Domain-Containing Integrin Xue Xiang PLOS ONE 11/28/2011 22140490 10.1371/journal.pone.0027946. More Info
Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface Veronika I. Zarnitsyna Journal of Visiualized Experiments 11/2/2011 22083316 10.3791/3519. More Info
Measuring Receptor-Ligand Binding Kinetics on Cell Surfaces: From Adhesion Frequency to Thermal Fluctuation Methods. Wei Chen Cellular and molecular bioengineering 9/27/2011 19890486 10.1007/s12195-008-0024-8 More Info
Membrane-based actuation for high-speed single molecule force spectroscopy studies using AFM. Sarangapani K. Eur Biophys J. 7/1/2010 20054686 10.1007/s00249-009-0575-1 More Info
Simulated Thermal Unfolding of the von Willebrand Factor A Domains Wei Chen Cell. Mol. Bioeng. 6/6/2010 None More Info
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness Jun Huang Nature 4/8/2010 20357766 10.1038/nature08944 More Info
Molecular Biomechanics: The Molecular Basis of How Forces Regulate Cellular Function Bao G Cell. Mol. Bioeng. 3/2/2010 20700472 10.1007/s12195-010-0109-z More Info
Force-induced cleavage of single VWF A1A2A3-tridomains by ADAMTS-13 Tao Wu Blood 1/14/2010 19897584 10.1182/blood-2009-03-210369 More Info
Dynamics of the interaction of human IgG subtype immune complexes with cells expressing R and H allelic forms of a low-affinity Fcgamma receptor CD32A Shashidharamurthy R. J Immunol. 12/29/2009 20007585 10.4049/jimmunol.0902550 More Info
Changes in thermodynamic stability of von Willebrand factor differentially affect the force-dependent binding to platelet GPIbalpha. Auton M Biophys J. 7/22/2009 19619477 10.1016/j.bpj.2009.05.009 More Info
Demonstration of catch bonds between an integrin and its ligand Fang Kong J Cell Biol 6/29/2009 19564406 10.1083/jcb.200810002 More Info
Molecular Dynamics Simulated Unfolding of von Willebrand Factor A domains by Force Wei Chen Cellular and Molecular Bioengineering 2/13/2009 None More Info
Bending rigidities of cell surface molecules P-selectin and PSGL-1 Fang Y J Biomech 2/9/2009 19144337 10.1016/j.jbiomech.2008.11.020 More Info
MHC Variant Peptide-Mediated Anergy of Encephalitogenic T Cells Requires SHP-1 Wasserman H. A. J. Immunol. 11/15/2008 18981103 10.4049/​jimmunol.181.10.6843 More Info
Flow induces loop-to-beta-hairpin transition on the beta-switch of platelet Glycoprotein Ibalpha Lou J. Proc. Natl. Acad. Sci. 9/16/2008 18772372 10.1073/pnas.0801965105 More Info
Binary Time Series Modeling With Application to Adhesion Frequency Experiments Hung Y J Am Stat Assoc 9/1/2008 22180690 More Info
Platelet Glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF Yago T. J. Clin. Invest. 9/1/2008 18725999 10.1172/JCI35754 More Info
Flow-Induced Structural Transition in the beta-switch Region of Glycoprotein Ib Chen Z. Biophys. J. 8/1/2008 18441028 10.1529/biophysj.108.132324 More Info
A Coupled Diffusion-Kinetics Model for Analysis of Contact Area FRAP Experiment Wu J. Biophys J. 7/1/2008 18390628 10.1529/biophysj.107.114439. More Info
Measuring Diffusion and Binding Kinetics by Contact Area FRAP Tolentino T. P. Biophys J. 7/1/2008 18390627 10.1529/biophysj.107.114447 More Info
The Differential Effect of Endothelial Cell Factors on In Vitro Motility of Malignant and Non-malignant Cell Wright A. Ann. Biomed. Eng 6/1/2008 18398681 10.1007/s10439-008-9489-9 More Info
Integrin Dependence of Calu-1 Cell Motility on Endothelial Extracellular Matrix Proteins Wright A. Ann. Biomed. Eng. 6/1/2008 18398683 10.1007/s10439-008-9456-5 More Info
Replacing a lectin-domain residue in L-selectin enhances binding to P-selectin Glycoprotein ligand-1 but not to 6-sulfo-sialyl Lewis X Klopocki A. G. J. Biol. Chem. 4/25/2008 18250165 10.1074/jbc.M709785200 More Info
Mechanisms for Flow-Enhanced Cell Adhesion Zhu C. Ann. Biomed. eng. 4/1/2008 18299992 10.1007/s10439-008-9464-5 More Info
Kinetics of MHC-CD8 interaction at the T cell membrane. Jun Huang Journal of immunology (Baltimore, Md. : 1950) 2/5/2008 18025211 None More Info
A nonsynonymous functional variant in integrin-alphaM (encoded by ITGAM) is associated with systemic lupus erythematosus Nath S. K. Nature Genet. 2/1/2008 18204448 10.1038/ng.71 More Info
Monitoring receptor-ligand interactions between surfaces by thermal fluctuations Chen W. Biophy. J 1/15/2008 17890399 10.1529/biophysj.107.117895 More Info
A catch to integrin activation. Rodger P McEver Nature immunology 11/27/2007 17878912 10.1038/ni1007-1035 More Info
Two stage cadherin kinetics require multiple extracellular domains but not the cytoplasmic region. Yuan-Hung Chien The Journal of biological chemistry 11/13/2007 17999960 10.1074/jbc.M708044200 More Info
Memory in receptor-ligand-mediated cell adhesion. Veronika I Zarnitsyna Proceedings of the National Academy of Sciences of the United States of America 11/8/2007 17991779 10.1073/pnas.0704811104 More Info
The Sliding–Rebinding Mechanism for Catch Bonds Jizhong Lou Japanese Journal of Applied Physics 8/23/2007 None 10.1143/JJAP.46.5528 More Info
A micromachined membrane-based active probe for biomolecular mechanics measurement Hamdi Torun Nanotechnology 3/23/2007 None 10.1088/0957-4484/18/16/165303 More Info
Affinity and kinetic analysis of Fcgamma receptor IIIa (CD16a) binding to IgG ligands. Ping Li The Journal of biological chemistry 1/3/2007 17202140 10.1074/jbc.M609064200 More Info
A structure-based sliding-rebinding mechanism for catch bonds. Jizhong Lou Biophysical journal 12/1/2006 17142266 10.1529/biophysj.106.097048 More Info
Flow-enhanced adhesion regulated by a selectin interdomain hinge. Jizhong Lou The Journal of cell biology 10/30/2006 17000883 10.1083/jcb.200606056 More Info
Transport governs flow-enhanced cell tethering through L-selectin at threshold shear. Tadayuki Yago Biophysical journal 10/6/2006 17028146 10.1529/biophysj.106.090969 More Info
Forces required to initiate membrane tether extrusion from cell surface depend on cell type but not on the surface molecule. Warren D Marcus Mechanics & chemistry of biosystems : MCB 7/17/2006 16783921 None More Info
Catch bonds: physical models, structural bases, biological function and rheological relevance. Cheng Zhu Biorheology 6/29/2006 16369083 None More Info
Catch bonds: physical models and biological functions. Cheng Zhu Molecular & cellular biomechanics : MCB 6/2/2006 16708472 None More Info
Thermo-mechanical responses of a surface-coupled AFM cantilever. Jianhua Wu Journal of biomechanical engineering 5/23/2006 16502663 None More Info
Probabilistic modeling of rosette formation. Mian Long Biophysical journal 4/7/2006 16603493 10.1529/biophysj.106.082909 More Info
Quantifying the effects of contact duration, loading rate, and approach velocity on P-selectin–PSGL-1 interactions using AFM Shouqin Lü Polymer 3/22/2006 None More Info
T cells like a firm molecular handshake. Michael L Dustin Proceedings of the National Academy of Sciences of the United States of America 3/13/2006 16537367 10.1073/pnas.0600899103 More Info
Measuring molecular elasticity by atomic force microscope cantilever fluctuations. Bryan T Marshall Biophysical journal 10/28/2005 16258054 10.1529/biophysj.105.061010 More Info
Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain. Fang Zhang The Journal of biological chemistry 10/18/2005 16234238 10.1074/jbc.M510407200 More Info
Force history dependence of receptor-ligand dissociation. Bryan T Marshall Biophysical journal 11/19/2004 15556978 10.1529/biophysj.104.050567 More Info
Catch bonds govern adhesion through L-selectin at threshold shear. Tadayuki Yago The Journal of cell biology 10/25/2004 15364963 10.1083/jcb.200403144 More Info
Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics. Jun Huang The Journal of biological chemistry 8/6/2004 15299021 10.1074/jbc.M407039200 More Info
Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond. Evan Evans Proceedings of the National Academy of Sciences of the United States of America 7/26/2004 15277675 10.1073/pnas.0401870101 More Info
Low force decelerates L-selectin dissociation from P-selectin glycoprotein ligand-1 and endoglycan. Krishna K Sarangapani The Journal of biological chemistry 10/22/2003 14573602 10.1074/jbc.M310396200 More Info
Direct observation of catch bonds involving cell-adhesion molecules. Bryan T Marshall Nature 6/17/2003 12736689 10.1038/nature01605 More Info
Measuring receptor/ligand interaction at the single-bond level: experimental and interpretative issues. Cheng Zhu Annals of biomedical engineering 12/27/2002 12051616 None More Info
Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow. Tadayuki Yago The Journal of cell biology 8/12/2002 12177042 10.1083/jcb.200204041 More Info
Kinetic measurements of cell surface E-selectin/carbohydrate ligand interactions. M Long Annals of biomedical engineering 6/12/2002 11791676 None More Info
Recombinant CD16A-Ig forms a homodimer and cross-blocks the ligand binding functions of neutrophil and monocyte Fcgamma receptors. Ping Li Molecular immunology 2/6/2002 11750654 None More Info
Identification of self through two-dimensional chemistry and synapses. M L Dustin Annual review of cell and developmental biology 1/15/2002 11687486 10.1146/annurev.cellbio.17.1.133 More Info
Cell mechanics: mechanical response, cell adhesion, and molecular deformation. C Zhu Annual review of biomedical engineering 1/2/2002 11701511 10.1146/annurev.bioeng.2.1.189 More Info
Diffusion of microspheres in shear flow near a wall: use to measure binding rates between attached molecules. A Pierres Biophysical journal 9/13/2001 11423392 10.1016/S0006-3495(01)75677-9 More Info
Tetramethylpyrazine inhibits phytohemagglutinin-induced upregulation of ICAM-1 and LFA-1 mediated leukocyte adhesion. H Zhao Clinical hemorheology and microcirculation 9/13/2001 11321434 None More Info
Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow. V Ramachandran Proceedings of the National Academy of Sciences of the United States of America 7/31/2001 11481445 10.1073/pnas.171248098 More Info
Quantifying the impact of membrane microtopology on effective two-dimensional affinity. T E Williams The Journal of biological chemistry 1/29/2001 11278674 10.1074/jbc.M010427200 More Info
Concurrent binding to multiple ligands: kinetic rates of CD16b for membrane-bound IgG1 and IgG2. T E Williams Biophysical journal 11/13/2000 11023891 10.1016/S0006-3495(00)76435-6 More Info
Concurrent and independent binding of Fcgamma receptors IIa and IIIb to surface-bound IgG. T E Williams Biophysical journal 11/13/2000 11023892 10.1016/S0006-3495(00)76436-8 More Info
Modeling concurrent binding of multiple molecular species in cell adhesion. C Zhu Biophysical journal 11/13/2000 11023890 10.1016/S0006-3495(00)76434-4 More Info
3Beta-hydroxy-6-aza-cholestane and related analogues as phosphatidylinositol specific phospholipase C (PI-PLC) inhibitors with antitumor activity. W Xie Bioorganic & medicinal chemistry 7/26/2000 10819158 None More Info
The membrane anchor influences ligand binding 2D kinetic rates and 3D affinity of FcγRIII (CD16) S.E. Chesla, P. Li, S. Nagarajan, P. Selvaraj, C. Zhu J Biol Chem 4/7/2000 None 10.1074/jbc.275.14.10235 More Info
Cell-specific, activation-dependent regulation of neutrophil CD32A ligand-binding function. S Nagarajan Blood 2/24/2000 10648424 None More Info
Analysis of competition binding between soluble and membrane-bound ligands for cell surface receptors. P Li Biophysical journal 2/14/2000 10585962 10.1016/S0006-3495(99)77171-7 More Info
A modified Boyden chamber assay for tumor cell transendothelial migration in vitro. Y H Li Clinical & experimental metastasis 2/7/2000 10651309 None More Info
Kinetics and mechanics of cell adhesion. C Zhu Journal of biomechanics 2/7/2000 10609515 None More Info
Tyrosine replacement in P-selectin glycoprotein ligand-1 affects distinct kinetic and mechanical properties of bonds with P- and L-selectin. V Ramachandran Proceedings of the National Academy of Sciences of the United States of America 1/6/2000 10570148 None More Info
Probabilistic modeling of shear-induced formation and breakage of doublets cross-linked by receptor-ligand bonds. M Long Biophysical journal 3/9/1999 9916043 10.1016/S0006-3495(99)77276-0 More Info
Measuring two-dimensional receptor-ligand binding kinetics by micropipette. S E Chesla Biophysical journal 11/30/1998 9726957 10.1016/S0006-3495(98)74074-3 More Info
Determining force dependence of two-dimensional receptor-ligand binding affinity by centrifugation. J W Piper Biophysical journal 4/2/1998 9449350 10.1016/S0006-3495(98)77807-5 More Info
Ligand binding and phagocytosis by CD16 (Fc gamma receptor III) isoforms. Phagocytic signaling by associated zeta and gamma subunits in Chinese hamster ovary cells. S Nagarajan The Journal of biological chemistry 12/14/1995 7592758 None More Info
Regulation of adhesion molecule expression in Kaposi's sarcoma cells. J Yang Journal of immunology (Baltimore, Md. : 1950) 1/12/1994 7504714 None More Info
Determination of adhesion force between single cell pairs generated by activated GpIIb-IIIa receptors. K L Sung Blood 2/23/1993 8422461 None More Info
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