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Mechanochemical coupling of formin-induced actin interaction at the level of single molecular complex. Zhenhai Li, Hyunjung Lee, Suzanne G. Eskin, Shoichiro Ono, Cheng Zhu, Larry V. McIntire Biomechanics and modeling in mechanobiology 1/21/2020 12525176 10.1007/s10237-019-01284-5 More Info
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A Generalized Gaussian Process Model for Computer Experiments With Binary Time Series Chih-Li Sung, Ying Hung, William Rittase, Cheng Zhu, C. F. Jeff Wu Journal of the American Statistical Association 5/28/2019 None 10.1080/01621459.2019.1604361 More Info
Abstract 3236: T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade Duane Moogk, Lin Wang, Kaitao Li, Zhou Yuan, Jeffrey Weber, Iman Osman, Cheng Zhu and Michelle Krogsgaard AACR; Cancer Res 3/29/2019 None 10.1158/1538-7445.AM2019-3236 More Info
An integrin αIIbβ3 intermediate affinity state mediates biomechanical platelet aggregation. Yunfeng Chen Nature materials 3/25/2019 30911119 10.1038/s41563-019-0323-6 More Info
Force-history dependence and cyclic mechanical reinforcement of actin filaments at the single molecular level. Hyunjung Lee, Suzanne G. Eskin, Shoichiro Ono, Cheng Zhu, Larry V. McIntire Journal of Cell Science 2/4/2019 30659118 10.1242/jcs.216911 More Info
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Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment. Gurpanna Saggu Nature communications 11/29/2018 23310953 10.1038/s41467-018-07506-1 More Info
A TCR mechanotransduction signaling loop induces negative selection in the thymus. Jinsung Hong Nature immunology 11/12/2018 30420628 10.1038/s41590-018-0259-z More Info
Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis. Xiaohong Ruby Xu Nature communications 9/6/2018 7923659 10.1038/s41467-018-05806-0 More Info
Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces. Palash K Dutta Nano letters 7/5/2018 27941751 10.1021/acs.nanolett.8b01374 More Info
Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces. Palash K Dutta Nano letters 7/5/2018 29911385 10.1021/acs.nanolett.8b01374 More Info
Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release and coagulation. Aiming Pang Blood 5/31/2018 29853537 10.1182/blood-2017-05-785253 More Info
Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets. Lining Ju Nature communications 3/14/2018 18071073 10.1038/s41467-018-03430-6 More Info
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Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases. Hiroshi Nishi The Journal of clinical investigation 9/11/2017 28891817 10.1172/JCI94039 More Info
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Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes. Lining Ju Methods in molecular biology (Clifton, N.J.) 3/3/2017 28255706 10.1007/978-1-4939-6881-7_15 More Info
Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity. Vincent C Luca Science (New York, N.Y.) 3/2/2017 28254785 10.1126/science.aaf9739 More Info
The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy. Guangheng Zhu Blood 1/25/2017 28122739 10.1182/blood-2016-07-729400 More Info
Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force. Padmaja Mehta-D'souza The Journal of biological chemistry 12/23/2016 28011641 10.1074/jbc.M116.767186 More Info
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Force regulated conformational change of integrin αVβ3. Yunfeng Chen Matrix biology : journal of the International Society for Matrix Biology 7/14/2016 27423389 10.1016/j.matbio.2016.07.002 More Info
Force regulated conformational change of integrin αVβ3. Yunfeng Chen Matrix biology : journal of the International Society for Matrix Biology 7/14/2016 27423389 10.1016/j.matbio.2016.07.002 More Info
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Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. David K Cole The Journal of clinical investigation 5/16/2016 27183389 10.1172/JCI85679 More Info
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Force-Induced Unfolding of Leucine-Rich Repeats of Glycoprotein Ibα Strengthens Ligand Interaction. Lining Ju Biophysical journal 11/5/2015 26536255 10.1016/j.bpj.2015.08.050 More Info
Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease. Jennifer D Hood Journal of immunology (Baltimore, Md. : 1950) 9/18/2015 26385521 10.4049/jimmunol.1501464 More Info
Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells. Jinsung Hong Journal of immunology (Baltimore, Md. : 1950) 9/2/2015 26336148 10.4049/jimmunol.1501407 More Info
Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell Yunfeng Chen J Vis Exp. 8/4/2015 26274371 10.3791/52975 More Info
Von Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kinetics. Lining Ju Thrombosis research 6/20/2015 26213126 10.1016/j.thromres.2015.06.019 More Info
Pre-TCR ligand binding impacts thymocyte development before αβTCR expression. Robert J Mallis Proceedings of the National Academy of Sciences of the United States of America 6/8/2015 26056289 10.1073/pnas.1504971112 More Info
The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex. Baoyu Liu European journal of immunology 5/22/2015 25944482 10.1002/eji.201445358 More Info
Transport regulation of two-dimensional receptor-ligand association. Lining Ju Biophysical journal 4/12/2015 25863068 10.1016/j.bpj.2015.02.023 More Info
A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force. Florencia Rosetti Cell reports 3/11/2015 25772353 10.1016/j.celrep.2015.02.037 More Info
Molecular force spectroscopy on cells. Baoyu Liu Annual review of physical chemistry 1/12/2015 25580628 10.1146/annurev-physchem-040214-121742 More Info
Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor. Javier Casas Nature communications 11/27/2014 25427562 10.1038/ncomms6624 More Info
DNA-based digital tension probes reveal integrin forces during early cell adhesion. Yun Zhang Nature communications 10/24/2014 25342432 10.1038/ncomms6167 More Info
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Dynamic catch of a Thy-1-α5β1+syndecan-4 trimolecular complex. Vincent F Fiore Nature communications 9/12/2014 25216363 10.1038/ncomms5886 More Info
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. Baoyu Liu Cell 7/17/2014 24725404 10.1016/j.cell.2014.02.053 More Info
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Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis. Young I Choi Proceedings of the National Academy of Sciences of the United States of America 12/16/2013 24344262 10.1073/pnas.1314209111 More Info
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The N-terminal flanking region of the A1 domain regulates the force-dependent binding of von Willebrand factor to platelet glycoprotein Ibα. Lining Ju The Journal of biological chemistry 9/23/2013 24062306 10.1074/jbc.M113.504001 More Info
Mechanochemitry: a molecular biomechanics view of mechanosensing. Cheng Zhu Annals of biomedical engineering 9/5/2013 24006131 10.1007/s10439-013-0904-5 More Info
Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling. Yolande Chen Blood 7/23/2013 23881916 10.1182/blood-2013-03-484550 More Info
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An HMM-based algorithm for evaluating rates of receptor-ligand binding kinetics from thermal fluctuation data. Lining Ju Bioinformatics (Oxford, England) 4/18/2013 23599504 10.1093/bioinformatics/btt180 More Info
Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds. Cho-yin Lee Proceedings of the National Academy of Sciences of the United States of America 3/4/2013 23460697 10.1073/pnas.1218407110 More Info
P-selectin glycoprotein ligand-1 forms dimeric interactions with E-selectin but monomeric interactions with L-selectin on cell surfaces. Yan Zhang PloS one 2/25/2013 23451187 10.1371/journal.pone.0057202 More Info
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Insights from in situ analysis of TCR–pMHC recognition: response of an interaction network Cheng Zhu Immunological Reviews 1/1/2013 23278740 10.1111/imr.12016. More Info
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