Dr. Muaz Rushdi

T cells are central in maintaining the body’s immunity against viral and bacterial infections, as well as against cancer. However, during these pathological states, T cells are immersed in an altered biochemical environment which influences how effective they are in protecting our bodies. I’m interested in examining how early signaling events of T cells are affected by adverse microenvironments that are common in various diseases.

Qu, N., Ma, Z., Zhang, M., Rushdi, M. N. , Krueger, C. J., & Chen, A. K. (2018). Inhibition of retroviral Gag assembly by non-silencing miRNAs promotes autophagic viral degradation. Protein & cell, 9(7), 640-651.

Dutta, P. K., Zhang, Y., Blanchard, A., Ge, C., Rushdi, M. , Weiss, K., ... & Salaita, K. (2018). Programmable multivalent DNA-origami tension probes for reporting cellular traction forces. Nano letters.

Yang, Y., Qu, N., Tan, J., Rushdi, M. N. , Krueger, C. J., & Chen, A. K. (2018). Roles of Gag-RNA interactions in HIV-1 virus assembly deciphered by single-molecule localization microscopy. Proceedings of the National Academy of Sciences, 201805728.

Wu, X., Mao, S., Yang, Y., Rushdi, M. N., Krueger, C. J., & Chen, A. K. (2018). A CRISPR/molecular beacon hybrid system for live-cell genomic imaging. Nucleic acids research.

Chen, Y., Ju, L., Rushdi, M. N., Ge, C., & Zhu, C. (2017). Receptor-mediated cell mechanosensing. Molecular Biology of the Cell, mbc-E17.

Qu, N., Ma, Z., Zhang, M., Rushdi, M. N., Krueger, C. J., & Chen, A. K. (2017). Inhibition of retroviral Gag assembly by non-silencing miRNAs promotes autophagic viral degradation. Protein & Cell, 1-12.

Ju, L., Chen, Y., Rushdi, M. N., Chen, W., & Zhu, C. (2017). Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes. The Immune Synapse: Methods and Protocols, 231-258.

Ge, C., Rushdi, Rushdi, M. N., & Zhu, C. (2016). T cells exert force for pMHC pull-ups. Translational Cancer Research, 5(4), S855-S857.

Ge, X. N., Ha, S. G., Rao, A., Greenberg, Y. G., Rushdi, M. N., Esko, J. D., ... & Sriramarao, P. (2014). Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model. Glycobiology, 24(8), 715-727.